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Metformin Ameliorates Senescence of Adipose-Derived Mesenchymal Stem Cells and Attenuates Osteoarthritis Progression via the AMPK-Dependent Autophagy Pathway
Osteoarthritis (OA) is one of the most serious age-related diseases worldwide that drastically affects the quality of life of patients. Despite advancements in the treatment of arthritis, especially with adipose-derived mesenchymal stem cells (ADSCs), senescence-induced alterations in ADSCs negative...
Autores principales: | Li, Zheng, Liu, Lin, Yang, Yanni, Zheng, Haishi, Cai, Yongsong, Ma, Yao, Gu, Ruiying, Xu, Ke, Zhang, Rui, Xu, Peng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9187432/ https://www.ncbi.nlm.nih.gov/pubmed/35693701 http://dx.doi.org/10.1155/2022/4620254 |
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