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In vivo visualization of fluorescence reflecting CDK4 activity in a breast cancer mouse model

The CDK4/6‐Rb axis is a crucial target of cancer therapy and several selective inhibitors of it have been approved for clinical application. However, current therapeutic efficacy evaluation mostly relies on anatomical imaging, which cannot directly reflect changes in drug targets, leading to a delay...

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Detalles Bibliográficos
Autores principales: Gao, Yi‐Yang, Yang, Rui‐Qin, Lou, Kang‐Liang, Dang, Yong‐Ying, Dong, Yuan‐Yuan, He, Yue‐Yang, Huang, Wen‐He, Chen, Min, Zhang, Guo‐Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9187519/
https://www.ncbi.nlm.nih.gov/pubmed/35711853
http://dx.doi.org/10.1002/mco2.136