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SLC26A9 deficiency causes gastric intraepithelial neoplasia in mice and aggressive gastric cancer in humans
BACKGROUND: Solute carrier family 26 member (SLC26A9) is a Cl(−) uniporter with very high expression levels in the gastric mucosa. Here, we describe morphological and molecular alterations in gastric mucosa of slc26a9(−/−) mice and in selective parietal cell-deleted slc26a9(fl/fl)/Atp4b-Cre mice and...
Autores principales: | Liu, Xuemei, Li, Taolang, Ma, Zhiyuan, Riederer, Brigitte, Yuan, Dumin, Zhu, Jiaxing, Li, Yunhua, An, Jiaxing, Wen, Guorong, Jin, Hai, Yang, Xiao, Seidler, Ursula, Tuo, Biguang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9187568/ https://www.ncbi.nlm.nih.gov/pubmed/35426084 http://dx.doi.org/10.1007/s13402-022-00672-x |
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