SS18-SSX drives CREB activation in synovial sarcoma

PURPOSE: Synovial sarcoma (SySa) is a rare soft tissue tumor characterized by a reciprocal t(X;18) translocation. The chimeric SS18-SSX fusion protein represents the major driver of the disease, acting as aberrant transcriptional dysregulator. Oncogenic mechanisms whereby SS18-SSX mediates sarcomage...

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Detalles Bibliográficos
Autores principales: Cyra, Magdalene, Schulte, Miriam, Berthold, Ruth, Heinst, Lorena, Jansen, Esther-Pia, Grünewald, Inga, Elges, Sandra, Larsson, Olle, Schliemann, Christoph, Steinestel, Konrad, Hafner, Susanne, Simmet, Thomas, Wardelmann, Eva, Kailayangiri, Sareetha, Rossig, Claudia, Isfort, Ilka, Trautmann, Marcel, Hartmann, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9187574/
https://www.ncbi.nlm.nih.gov/pubmed/35556229
http://dx.doi.org/10.1007/s13402-022-00673-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9187574/
https://www.ncbi.nlm.nih.gov/pubmed/35556229
http://dx.doi.org/10.1007/s13402-022-00673-w

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