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Assessing sequence-based protein–protein interaction predictors for use in therapeutic peptide engineering

Engineering peptides to achieve a desired therapeutic effect through the inhibition of a specific target activity or protein interaction is a non-trivial task. Few of the existing in silico peptide design algorithms generate target-specific peptides. Instead, many methods produce peptides that achie...

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Detalles Bibliográficos
Autores principales: Charih, François, Biggar, Kyle K., Green, James R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9187631/
https://www.ncbi.nlm.nih.gov/pubmed/35688894
http://dx.doi.org/10.1038/s41598-022-13227-9