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Iridium-catalyzed direct asymmetric reductive amination utilizing primary alkyl amines as the N-sources

Direct asymmetric reductive amination is one of the most efficient methods for the construction of chiral amines, in which the scope of the applicable amine coupling partners remains a significant challenge. In this study we describe primary alkyl amines effectively serve as the N-sources in direct...

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Detalles Bibliográficos
Autores principales: Wu, Zitong, Wang, Wenji, Guo, Haodong, Gao, Guorui, Huang, Haizhou, Chang, Mingxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9187633/
https://www.ncbi.nlm.nih.gov/pubmed/35688909
http://dx.doi.org/10.1038/s41467-022-31045-5