Cis- and trans-resveratrol have opposite effects on histone serine-ADP-ribosylation and tyrosine induced neurodegeneration

Serum tyrosine levels increase during aging, neurocognitive, metabolic, and cardiovascular disorders. However, calorie restriction (CR) and sleep lower serum tyrosine levels. We previously showed that tyrosine inhibits tyrosyl-tRNA synthetase (TyrRS)-mediated activation of poly-ADP-ribose polymerase...

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Detalles Bibliográficos
Autores principales: Jhanji, Megha, Rao, Chintada Nageswara, Massey, Jacob C., Hope, Marion C., Zhou, Xueyan, Keene, C. Dirk, Ma, Tao, Wyatt, Michael D., Stewart, Jason A., Sajish, Mathew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9187644/
https://www.ncbi.nlm.nih.gov/pubmed/35688816
http://dx.doi.org/10.1038/s41467-022-30785-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9187644/
https://www.ncbi.nlm.nih.gov/pubmed/35688816
http://dx.doi.org/10.1038/s41467-022-30785-8

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