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Maximum depth sequencing reveals an ON/OFF replication slippage switch and apparent in vivo selection for bifidobacterial pilus expression

The human gut microbiome, of which the genus Bifidobacterium is a prevalent and abundant member, is thought to sustain and enhance human health. Several surface-exposed structures, including so-called sortase-dependent pili, represent important bifidobacterial gut colonization factors. Here we show...

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Detalles Bibliográficos
Autores principales: Penno, Christophe, Motherway, Mary O’Connell, Fu, Yuan, Sharma, Virag, Crispie, Fiona, Cotter, Paul D., Houeix, Benoit, Joshi, Lokesh, Bottacini, Francesca, O’Dwyer, Aoife, Loughran, Gary, Atkins, John F., van Sinderen, Douwe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9187656/
https://www.ncbi.nlm.nih.gov/pubmed/35688912
http://dx.doi.org/10.1038/s41598-022-13668-2