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Mirror-image streptavidin with specific binding to L-biotin, the unnatural enantiomer
The streptavidin–biotin system is known to have a very high affinity and specificity and is widely used in biochemical immunoassays and diagnostics. However, this method is affected by endogenous D-biotin in serum sample measurements (biotin interference). While several efforts using alternative hig...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9187662/ https://www.ncbi.nlm.nih.gov/pubmed/35688934 http://dx.doi.org/10.1038/s41598-022-13763-4 |