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The protective effects of systemic dexamethasone on sensory epithelial damage and hearing loss in targeted Cx26-null mice

Mutations in the GJB2 gene (encoding Connexin26(Cx26)) are the most common cause of hereditary deafness, accounting for about a quarter of all cases. Sensory epithelial damage is considered to be one of the main causes of deafness caused by GJB2 gene mutation. Dexamethasone (DEX) is widely used in t...

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Detalles Bibliográficos
Autores principales: Xu, Kai, Chen, Sen, Xie, Le, Qiu, Yue, Liu, Xiao-zhou, Bai, Xue, Jin, Yuan, Wang, Xiao-hui, Sun, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9187686/
https://www.ncbi.nlm.nih.gov/pubmed/35688810
http://dx.doi.org/10.1038/s41419-022-04987-3