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Telomere-to-telomere human DNA replication timing profiles

The spatiotemporal organization of DNA replication produces a highly robust and reproducible replication timing profile. Sequencing-based methods for assaying replication timing genome-wide have become commonplace, but regions of high repeat content in the human genome have remained refractory to an...

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Detalles Bibliográficos
Autores principales: Massey, Dashiell J., Koren, Amnon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9187705/
https://www.ncbi.nlm.nih.gov/pubmed/35688856
http://dx.doi.org/10.1038/s41598-022-13638-8