MIF homolog d-dopachrome tautomerase (D-DT/MIF-2) does not inhibit accumulation and toxicity of misfolded SOD1

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by loss of upper and lower motor neurons. About 20% of familial ALS cases are caused by dominant mutations in SOD1. It has been suggested that toxicity of mutant SOD1 results from its misfolding, however, it is un...

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Detalles Bibliográficos
Autores principales: Alaskarov, Amina, Barel, Shir, Bakavayev, Shamchal, Kahn, Joy, Israelson, Adrian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9187739/
https://www.ncbi.nlm.nih.gov/pubmed/35688953
http://dx.doi.org/10.1038/s41598-022-13744-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9187739/
https://www.ncbi.nlm.nih.gov/pubmed/35688953
http://dx.doi.org/10.1038/s41598-022-13744-7

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