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Estimating intraclonal heterogeneity and subpopulation changes from bulk expression profiles in CMap
The connectivity among signatures upon perturbations curated in the CMap library provides a valuable resource for understanding therapeutic pathways and biological processes associated with the drugs and diseases. However, because of the nature of bulk-level expression profiling by the L1000 assay,...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Life Science Alliance LLC
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9187873/ https://www.ncbi.nlm.nih.gov/pubmed/35688486 http://dx.doi.org/10.26508/lsa.202101299 |