Factor VII, EPCR, aPC Modulators: novel treatment for neuroinflammation

BACKGROUND: Inflammation and coagulation are linked and pathogenic in neuroinflammatory diseases. Protease-activated receptor 1 (PAR1) can be activated both by thrombin, inducing increased inflammation, and activated protein C (aPC), inducing decreased inflammation. Modulation of the aPC-PAR1 pathwa...

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Detalles Bibliográficos
Autores principales: Golderman, Valery, Ben-Shimon, Marina, Maggio, Nicola, Dori, Amir, Gofrit, Shany Guly, Berkowitz, Shani, Qassim, Lamis, Artan-Furman, Avital, Zeimer, Talya, Chapman, Joab, Shavit-Stein, Efrat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9187898/
https://www.ncbi.nlm.nih.gov/pubmed/35690769
http://dx.doi.org/10.1186/s12974-022-02505-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9187898/
https://www.ncbi.nlm.nih.gov/pubmed/35690769
http://dx.doi.org/10.1186/s12974-022-02505-y

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