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Factor VII, EPCR, aPC Modulators: novel treatment for neuroinflammation

BACKGROUND: Inflammation and coagulation are linked and pathogenic in neuroinflammatory diseases. Protease-activated receptor 1 (PAR1) can be activated both by thrombin, inducing increased inflammation, and activated protein C (aPC), inducing decreased inflammation. Modulation of the aPC-PAR1 pathwa...

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Detalles Bibliográficos
Autores principales:	Golderman, Valery, Ben-Shimon, Marina, Maggio, Nicola, Dori, Amir, Gofrit, Shany Guly, Berkowitz, Shani, Qassim, Lamis, Artan-Furman, Avital, Zeimer, Talya, Chapman, Joab, Shavit-Stein, Efrat
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9187898/ https://www.ncbi.nlm.nih.gov/pubmed/35690769 http://dx.doi.org/10.1186/s12974-022-02505-y

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