Inclusion of a dual signal sequence enhances the immunogenicity of a novel viral vectored vaccine against the capsular group B meningococcus

BACKGROUND: Disease caused by the capsular group B meningococcus (MenB) is the leading cause of infectious death in UK infants. A novel adenovirus-based vaccine encoding the MenB factor H binding protein (fHbp) with an N-terminal dual signal sequence induces high titres of protective antibody after...

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Detalles Bibliográficos
Autores principales: Sheerin, Dylan, Dold, Christina, Silva-Reyes, Laura, Linder, Aline, Pollard, Andrew J., Rollier, Christine S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9187930/
https://www.ncbi.nlm.nih.gov/pubmed/35690803
http://dx.doi.org/10.1186/s13578-022-00809-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9187930/
https://www.ncbi.nlm.nih.gov/pubmed/35690803
http://dx.doi.org/10.1186/s13578-022-00809-3

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