Potential Therapeutic Role of Bone Morphogenic Protein 7 (BMP7) in the Pathogenesis of Graves’ Orbitopathy

PURPOSE: We investigated a role of bone morphogenic protein 7 (BMP7), a member of the TGF-β superfamily on pathogenic mechanism of Graves’ orbitopathy (GO). The therapeutic effects of BMP7 on inflammation and fibrosis were evaluated in cultured Graves’ orbital fibroblasts. METHODS: Expression of BMP...

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Detalles Bibliográficos
Autores principales: Kim, Bo Yi, Choi, Soo Hyun, Kim, Ji-Young, Ko, JaeSang, Yook, Jong In, Kim, Hyun Sil, Lee, Eun Jig, Kikkawa, Don O., Yoon, Jin Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2022
Materias:
Biochemistry and Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9187939/
https://www.ncbi.nlm.nih.gov/pubmed/35671049
http://dx.doi.org/10.1167/iovs.63.6.7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9187939/
https://www.ncbi.nlm.nih.gov/pubmed/35671049
http://dx.doi.org/10.1167/iovs.63.6.7

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