Microvolume Analysis of Aflibercept in Aqueous Humor Using Mass Spectrometry

PURPOSE: To develop a microvolume analytical method for measurement of the aflibercept concentration in human intraocular fluid and plasma. METHODS: We analyzed trace amounts of aflibercept in human aqueous humor using Fab-selective proteolysis and nano-surface and molecular-orientation limited (nSM...

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Detalles Bibliográficos
Autores principales: Kimura, Natsuka, Takahashi, Hidenori, Sakamoto, Shinichi, Yanagi, Yasuo, Maeshima, Nozomi, Minamimoto, Ayaka, Iwamoto, Noriko, Shimada, Takashi, Nagai, Ryozo, Aizawa, Kenichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9187940/
https://www.ncbi.nlm.nih.gov/pubmed/35671043
http://dx.doi.org/10.1167/tvst.11.6.7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9187940/
https://www.ncbi.nlm.nih.gov/pubmed/35671043
http://dx.doi.org/10.1167/tvst.11.6.7

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