Effect of SPARC Suppression in Mice, Perfused Human Anterior Segments, and Trabecular Meshwork Cells

PURPOSE: Secreted protein, acidic and rich in cysteine (SPARC) elevates intraocular pressure (IOP), increases certain structural extracellular matrix (ECM) proteins in the juxtacanalicular trabecular meshwork (JCT), and decreases matrix metalloproteinase (MMP) protein levels in trabecular meshwork (...

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Detalles Bibliográficos
Autores principales: MacDonald, William W., Swaminathan, Swarup S., Heo, Jae Young, Castillejos, Alexandra, Hsueh, Jessica, Liu, Brian J., Jo, Diane, Du, Annie, Lee, Hyunpil, Kang, Min Hyung, Rhee, Douglas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2022
Materias:
Glaucoma
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9187959/
https://www.ncbi.nlm.nih.gov/pubmed/35671048
http://dx.doi.org/10.1167/iovs.63.6.8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9187959/
https://www.ncbi.nlm.nih.gov/pubmed/35671048
http://dx.doi.org/10.1167/iovs.63.6.8

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