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Neuroprotective effects of ex vivo-expanded regulatory T cells on trimethyltin-induced neurodegeneration in mice

BACKGROUND: Trimethyltin (TMT) is a potent neurotoxicant that leads to hippocampal neurodegeneration. Regulatory T cells (Tregs) play an important role in maintaining the immune balance in the central nervous system (CNS), but their activities are impaired in neurodegenerative diseases. In this stud...

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Detalles Bibliográficos
Autores principales: Park, Seon-Young, Yang, HyeJin, Ye, Minsook, Liu, Xiao, Shim, Insop, Chang, Young-Tae, Bae, Hyunsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9188044/
https://www.ncbi.nlm.nih.gov/pubmed/35690816
http://dx.doi.org/10.1186/s12974-022-02512-z