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Adipose-derived stromal cells increase the formation of collagens through paracrine and juxtacrine mechanisms in a fibroblast co-culture model utilizing macromolecular crowding

BACKGROUND: Adipose-derived stromal cells (ASCs) possess a multitude of regenerative capabilities, which include immunomodulation, angiogenesis, and stimulation of extracellular matrix (ECM) remodeling. However, the underlying mechanisms leading to ECM remodeling remain largely elusive and highlight...

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Detalles Bibliográficos
Autores principales: Søndergaard, Rebekka Harary, Højgaard, Lisbeth Drozd, Reese-Petersen, Alexander Lynge, Hoeeg, Cecilie, Mathiasen, Anders Bruun, Haack-Sørensen, Mandana, Follin, Bjarke, Genovese, Federica, Kastrup, Jens, Juhl, Morten, Ekblond, Annette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9188050/
https://www.ncbi.nlm.nih.gov/pubmed/35690799
http://dx.doi.org/10.1186/s13287-022-02923-y