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Both prokaryotes and eukaryotes produce an immune response against plasmids with 5ʹ-GTTTGTT-3ʹ

In the evolutionary “arms race” from prokaryotes to eukaryotes, some memories of foreign DNA have been conserved for defensive purposes. Shortly after invasion by the plasmid, pEGFP-N1, the conserved the defense gene, isg15, was activated in the zebrafish zygote and in mammalian cells. Based on the...

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Detalles Bibliográficos
Autores principales: Li, Nan, Jiang, Dongya, He, Luqingqing, Yue, Yunyun, Zhang, Qinxin, Wang, Shuang, Zhang, Yunfeng, Wei, Yuxuan, Zhao, Qingshun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9188160/
https://www.ncbi.nlm.nih.gov/pubmed/35690839
http://dx.doi.org/10.1186/s13578-022-00825-3