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Persistent cortical and white matter inflammation after therapeutic hypothermia for ischemia in near-term fetal sheep

BACKGROUND: Therapeutic hypothermia significantly improves outcomes after moderate–severe hypoxic-ischemic encephalopathy (HIE), but it is partially effective. Although hypothermia is consistently associated with reduced microgliosis, it is still unclear whether it normalizes microglial morphology a...

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Detalles Bibliográficos
Autores principales: Zhou, Kelly Q., Bennet, Laura, Wassink, Guido, McDouall, Alice, Curtis, Maurice A., Highet, Blake, Stevenson, Taylor J., Gunn, Alistair J., Davidson, Joanne O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9188214/
https://www.ncbi.nlm.nih.gov/pubmed/35690757
http://dx.doi.org/10.1186/s12974-022-02499-7