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Effect of rottlerin on astrocyte phenotype polarization after trimethyltin insult in the dentate gyrus of mice

BACKGROUND: It has been demonstrated that reactive astrocytes can be polarized into pro-inflammatory A1 phenotype or anti-inflammatory A2 phenotype under neurotoxic and neurodegenerative conditions. Microglia have been suggested to play a critical role in astrocyte phenotype polarization by releasin...

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Detalles Bibliográficos
Autores principales: Hwang, Yeonggwang, Kim, Hyoung-Chun, Shin, Eun-Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9188234/
https://www.ncbi.nlm.nih.gov/pubmed/35690821
http://dx.doi.org/10.1186/s12974-022-02507-w