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Effect of rottlerin on astrocyte phenotype polarization after trimethyltin insult in the dentate gyrus of mice
BACKGROUND: It has been demonstrated that reactive astrocytes can be polarized into pro-inflammatory A1 phenotype or anti-inflammatory A2 phenotype under neurotoxic and neurodegenerative conditions. Microglia have been suggested to play a critical role in astrocyte phenotype polarization by releasin...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9188234/ https://www.ncbi.nlm.nih.gov/pubmed/35690821 http://dx.doi.org/10.1186/s12974-022-02507-w |