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In Vitro Generation of BK polyomavirus-specific T cells for adoptive cell therapy in refractory cystitis hemorrhagic patients after hematopoietic stem cell transplantation

INTRODUCTION: BKPyV associated hemorrhagic cystitis (BKPyV-HC) is a major and prevalent outcome of hematopoietic stem cell transplantation (HSCT) with no standard treatment option. Adoptive T cell therapy (ACT) against transplant-associated viruses has shown promising potential. We sought to produce...

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Detalles Bibliográficos
Autores principales: Najafabadi, Maryam Mohammadi, Soleimani, Masoud, Ahmadvand, Mohammad, Zomorrod, Mina Soufi, Mousavi, Seied Asadollah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9188250/
https://www.ncbi.nlm.nih.gov/pubmed/35689183
http://dx.doi.org/10.1186/s12865-022-00497-1