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Reduced expression of dopamine D2 receptors on astrocytes in R6/1 HD mice and HD post-mortem tissue

Dysfunction of the central dopaminergic system is thought to contribute to some of the clinical features of Huntington’s disease (HD), and dopamine (DA) receptor antagonists are commonly used to good effect in its treatment. It is well established that there is an early significant reduction in neur...

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Detalles Bibliográficos
Autores principales: Harris, Kate L., Mason, Sarah L., Vallin, Benjamin, Barker, Roger A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Scientific Publishers Ireland 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9188264/
https://www.ncbi.nlm.nih.gov/pubmed/34637857
http://dx.doi.org/10.1016/j.neulet.2021.136289