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Reduced expression of dopamine D2 receptors on astrocytes in R6/1 HD mice and HD post-mortem tissue
Dysfunction of the central dopaminergic system is thought to contribute to some of the clinical features of Huntington’s disease (HD), and dopamine (DA) receptor antagonists are commonly used to good effect in its treatment. It is well established that there is an early significant reduction in neur...
Autores principales: | Harris, Kate L., Mason, Sarah L., Vallin, Benjamin, Barker, Roger A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Scientific Publishers Ireland
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9188264/ https://www.ncbi.nlm.nih.gov/pubmed/34637857 http://dx.doi.org/10.1016/j.neulet.2021.136289 |
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