Development and validation of a paper spray mass spectrometry method for the rapid quantitation of remdesivir and its active metabolite, GS-441524, in human plasma

INTRODUCTION: Remdesivir (GS-5734) is a nucleoside analog prodrug with antiviral activity against several single-stranded RNA viruses, including the novel severe respiratory distress syndrome virus 2 (SARS-CoV-2). It is currently the only FDA-approved antiviral agent for the treatment of individuals...

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Detalles Bibliográficos
Autores principales: Skaggs, Christine, Zimmerman, Hannah, Manicke, Nicholas, Kirkpatrick, Lindsey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Articles from the Special issue on Advances in MS Instrumentation: The Present and Future of the Clinical Lab Edited by Phillip Mach and Christopher Chouinard
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9188284/
https://www.ncbi.nlm.nih.gov/pubmed/35721272
http://dx.doi.org/10.1016/j.jmsacl.2022.06.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9188284/
https://www.ncbi.nlm.nih.gov/pubmed/35721272
http://dx.doi.org/10.1016/j.jmsacl.2022.06.001

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