The Combination of Betahistine and Oxybutynin Increases Respiratory Control Sensitivity (Loop Gain) in People with Obstructive Sleep Apnea: A Randomized, Placebo-Controlled Trial

RATIONALE: There are widespread histaminergic projections throughout the brain, including hypoglossal nuclei, that modulate pharyngeal muscle tone and respiratory control. Hence, histaminergic stimulation pharmacologically may increase pharyngeal muscle tone and stabilize respiratory control (loop g...

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Detalles Bibliográficos
Autores principales: Messineo, Ludovico, Loffler, Kelly, Chiang, Alan, Osman, Amal, Taranto-Montemurro, Luigi, Eckert, Danny J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9188336/
https://www.ncbi.nlm.nih.gov/pubmed/35698591
http://dx.doi.org/10.2147/NSS.S362205

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9188336/
https://www.ncbi.nlm.nih.gov/pubmed/35698591
http://dx.doi.org/10.2147/NSS.S362205

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