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From the tyrosine hydroxylase hypothesis of Parkinson’s disease to modern strategies: a short historical overview
A time span of 60 years covers the detection of catecholamines in the brain, their function in movement and correlation to Parkinson’s disease (PD). The clinical findings that orally given l-DOPA can alleviate or even prevent akinesia gave great hope for the treatment of PD. Attention focused on the...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer Vienna
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9188506/ https://www.ncbi.nlm.nih.gov/pubmed/35460433 http://dx.doi.org/10.1007/s00702-022-02488-3 |