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Endoplasmic reticulum stress-induced release and binding of calreticulin from human ovarian cancer cells

BACKGROUND: Calreticulin (CRT) is an endoplasmic reticulum (ER) chaperone, but can appear surface bound on cancers cells, including ovarian cancers (OC). We investigated at what stage of cell viability, CRT appeared associated with surface of human OC cells. CRT on pre-apoptotic tumour cells is thou...

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Detalles Bibliográficos
Autores principales: Abdullah, Trefa M., Whatmore, Jacqueline, Bremer, Edwin, Slibinskas, Rimantas, Michalak, Marek, Eggleton, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9188521/
https://www.ncbi.nlm.nih.gov/pubmed/34800147
http://dx.doi.org/10.1007/s00262-021-03072-6