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TGF-β orchestrates the phenotype and function of monocytic myeloid-derived suppressor cells in colorectal cancer

BACKGROUND: Monocytic myeloid-derived suppressor cells (M-MDSCs) are significantly expanded in the blood of colorectal cancer (CRC) patients. However, their presence and underlying mechanisms in the tumour microenvironment of CRC have not been examined in detail. METHODS: Tumour tissues and peripher...

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Detalles Bibliográficos
Autores principales: Gneo, Luciana, Rizkalla, Nagy, Hejmadi, Rahul, Mussai, Francis, de Santo, Carmela, Middleton, Gary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9188538/
https://www.ncbi.nlm.nih.gov/pubmed/34727230
http://dx.doi.org/10.1007/s00262-021-03081-5