Design, synthesis and evaluation of novel tetrahydropyridothienopyrimidin-ureas as cytotoxic and anti-angiogenic agents

The novel derivatives of tetrahydropyridothienopyrimidine-based compounds have been designed and efficiently synthesized with good yields through seven steps reaction. The anticancer activity of compounds 11a-y has been evaluated against MCF-7, PC-3, HEPG-2, SW-480, and HUVEC cell lines by MTT assay...

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Detalles Bibliográficos
Autores principales: Motahari, Rasoul, Boshagh, Mohammad Amin, Moghimi, Setareh, Peytam, Fariba, Hasanvand, Zaman, Oghabi Bakhshaiesh, Tayebeh, Foroumadi, Roham, Bijanzadeh, Hamidreza, Firoozpour, Loghman, Khalaj, Ali, Esmaeili, Rezvan, Foroumadi, Alireza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9188586/
https://www.ncbi.nlm.nih.gov/pubmed/35690595
http://dx.doi.org/10.1038/s41598-022-13515-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9188586/
https://www.ncbi.nlm.nih.gov/pubmed/35690595
http://dx.doi.org/10.1038/s41598-022-13515-4

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