Targeting SARS-CoV-2 non-structural protein 13 via helicase-inhibitor-repurposing and non-structural protein 16 through pharmacophore-based screening

Novel drug compound hunting was carried out for SARS-CoV-2 proteins with low mutation susceptibility. The probability of escape mutation and drug resistance is lower if conserved microbial proteins are targeted by therapeutic drugs. Mutation rate of all SARS-CoV-2 proteins were analyzed via multiple...

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Detalles Bibliográficos
Autores principales: Samdani, Md. Nazmus, Morshed, Niaz, Reza, Rumman, Asaduzzaman, Muhammad, Islam, Abul Bashar Mir Md. Khademul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9188638/
https://www.ncbi.nlm.nih.gov/pubmed/35690957
http://dx.doi.org/10.1007/s11030-022-10468-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9188638/
https://www.ncbi.nlm.nih.gov/pubmed/35690957
http://dx.doi.org/10.1007/s11030-022-10468-8

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