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STING is an intrinsic checkpoint inhibitor that restrains the T(H)17 cell pathogenic program
External and intrinsic factors regulate the transcriptional profile of T helper 17 (T(H)17) cells, thereby affecting their pathogenic potential and revealing their context-dependent plasticity. The stimulator of interferon genes (STING), a component of the intracellular DNA-sensing pathway, triggers...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9188824/ https://www.ncbi.nlm.nih.gov/pubmed/35613599 http://dx.doi.org/10.1016/j.celrep.2022.110838 |