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STING is an intrinsic checkpoint inhibitor that restrains the T(H)17 cell pathogenic program
External and intrinsic factors regulate the transcriptional profile of T helper 17 (T(H)17) cells, thereby affecting their pathogenic potential and revealing their context-dependent plasticity. The stimulator of interferon genes (STING), a component of the intracellular DNA-sensing pathway, triggers...
Autores principales: | Damasceno, Luis Eduardo Alves, Cebinelli, Guilherme Cesar Martelossi, Fernandes, Mariane Font, Nascimento, Daniele Carvalho, Públio, Gabriel Azevedo, Vinolo, Marco Aurélio Ramirez, Oliveira, Sergio Costa, Sparwasser, Tim, Cunha, Thiago Mattar, Cunha, Fernando Queiroz, Alves-Filho, José Carlos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9188824/ https://www.ncbi.nlm.nih.gov/pubmed/35613599 http://dx.doi.org/10.1016/j.celrep.2022.110838 |
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