KNIME workflow for retrieving causal drug and protein interactions, building networks, and performing topological enrichment analysis demonstrated by a DILI case study

As an alternative to one drug-one target approaches, systems biology methods can provide a deeper insight into the holistic effects of drugs. Network-based approaches are tools of systems biology, that can represent valuable methods for visualizing and analysing drug-protein and protein–protein inte...

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Detalles Bibliográficos
Autores principales: Füzi, Barbara, Malik-Sheriff, Rahuman S., Manners, Emma J., Hermjakob, Henning, Ecker, Gerhard F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9188852/
https://www.ncbi.nlm.nih.gov/pubmed/35692045
http://dx.doi.org/10.1186/s13321-022-00615-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9188852/
https://www.ncbi.nlm.nih.gov/pubmed/35692045
http://dx.doi.org/10.1186/s13321-022-00615-6

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