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KNIME workflow for retrieving causal drug and protein interactions, building networks, and performing topological enrichment analysis demonstrated by a DILI case study
As an alternative to one drug-one target approaches, systems biology methods can provide a deeper insight into the holistic effects of drugs. Network-based approaches are tools of systems biology, that can represent valuable methods for visualizing and analysing drug-protein and protein–protein inte...
Autores principales: | Füzi, Barbara, Malik-Sheriff, Rahuman S., Manners, Emma J., Hermjakob, Henning, Ecker, Gerhard F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9188852/ https://www.ncbi.nlm.nih.gov/pubmed/35692045 http://dx.doi.org/10.1186/s13321-022-00615-6 |
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