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Effect of cytochrome P450 3A5 polymorphism on the pharmacokinetics of tacrolimus in renal transplant recipients

BACKGROUND: Renal transplant is an effective treatment option for end-stage kidney disease and tacrolimus is one of the most commonly used immunosuppressant drugs in renal transplant patients. Tacrolimus is a substrate of cytochrome P450 3A5 (CYP3A5), and a narrow therapeutic index and large inter-i...

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Detalles Bibliográficos
Autores principales: Htun, Yi Yi, Than, Nwe Nwe, Swe, Htar Kyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Transplantation 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9188947/
https://www.ncbi.nlm.nih.gov/pubmed/35770260
http://dx.doi.org/10.4285/kjt.2020.34.1.24