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Targeted deletion of Interleukin-3 results in asthma exacerbations

The cytokine interleukin-3 (IL-3) acts on early hematopoietic precursor cells. In humans, T(reg) cells secrete IL-3 and repress inflammatory cells except for basophils. The present study aims to elucidate the contribution of IL-3 in the development and the course of allergic asthma. We therefore ana...

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Detalles Bibliográficos
Autores principales: Kölle, Julia, Zimmermann, Theodor, Kiefer, Alexander, Rieker, Ralf J., Xepapadaki, Paraskevi, Zundler, Sebastian, Papadopoulos, Nikolaos G., Finotto, Susetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9189047/
https://www.ncbi.nlm.nih.gov/pubmed/35707726
http://dx.doi.org/10.1016/j.isci.2022.104440