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Single-cell analysis reveals X upregulation is not global in pre-gastrulation embryos

In mammals, transcriptional inactivation of one X chromosome in female compensates for the dosage of X-linked gene expression between the sexes. Additionally, it is believed that the upregulation of active X chromosome in male and female balances the dosage of X-linked gene expression relative to au...

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Detalles Bibliográficos
Autores principales: Naik, Hemant Chandru, Hari, Kishore, Chandel, Deepshikha, Jolly, Mohit Kumar, Gayen, Srimonta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9189126/
https://www.ncbi.nlm.nih.gov/pubmed/35707719
http://dx.doi.org/10.1016/j.isci.2022.104465