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Single-cell analysis reveals X upregulation is not global in pre-gastrulation embryos
In mammals, transcriptional inactivation of one X chromosome in female compensates for the dosage of X-linked gene expression between the sexes. Additionally, it is believed that the upregulation of active X chromosome in male and female balances the dosage of X-linked gene expression relative to au...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9189126/ https://www.ncbi.nlm.nih.gov/pubmed/35707719 http://dx.doi.org/10.1016/j.isci.2022.104465 |