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Copy number gains of chromosome 17 identified by dual in situ hybridization in non-small cell lung cancer tissue correlate with overexpression of c-Myc

BACKGROUND: c-Myc regulates multiple genes involved in cell proliferation in various cancer types including non-small cell lung cancer (NSCLC). Copy number gains of cytoband 17q25.3, along with chromosome 17, have been reported in NSCLC patients, emphasizing the clinical significance as a potential...

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Detalles Bibliográficos
Autores principales: Sunpaweravong, Patrapim, Thongwatchara, Patcharaporn, Chotipanvithayakul, Rassamee, Sangkhathat, Surasak, Thongsuksai, Paramee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9189177/
https://www.ncbi.nlm.nih.gov/pubmed/35706805
http://dx.doi.org/10.21037/tcr-21-2705