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Allicin affects the pharmacokinetics of sulfadiazine and florfenicol by downregulating the expression of jejunum P-gp and BCRP in broilers

Allicin, one of the main bioactive compounds in garlic, is an excellent feed additive. It is unknown whether allicin affects the expression of P-gp and BCRP, 2 important ABC efflux transporters related to the pharmacokinetics of antimicrobials in chickens. In this study, by bidirectional transport t...

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Detalles Bibliográficos
Autores principales: Wang, Xiaoming, Wang, Yue, Fang, Ci, Gong, Qianmei, Huang, Jinhu, Zhang, Yujuan, Wang, Liping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9189214/
https://www.ncbi.nlm.nih.gov/pubmed/35688033
http://dx.doi.org/10.1016/j.psj.2022.101947