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Allicin affects the pharmacokinetics of sulfadiazine and florfenicol by downregulating the expression of jejunum P-gp and BCRP in broilers
Allicin, one of the main bioactive compounds in garlic, is an excellent feed additive. It is unknown whether allicin affects the expression of P-gp and BCRP, 2 important ABC efflux transporters related to the pharmacokinetics of antimicrobials in chickens. In this study, by bidirectional transport t...
Autores principales: | Wang, Xiaoming, Wang, Yue, Fang, Ci, Gong, Qianmei, Huang, Jinhu, Zhang, Yujuan, Wang, Liping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9189214/ https://www.ncbi.nlm.nih.gov/pubmed/35688033 http://dx.doi.org/10.1016/j.psj.2022.101947 |
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