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Direct anabolic metabolism of three-carbon propionate to a six-carbon metabolite occurs in vivo across tissues and species

Anabolic metabolism of carbon in mammals is mediated via the one- and two-carbon carriers S-adenosyl methionine and acetyl-coenzyme A. In contrast, anabolic metabolism of three-carbon units via propionate has not been shown to extensively occur. Mammals are primarily thought to oxidize the three-car...

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Detalles Bibliográficos
Autores principales: Doan, Mary T., Neinast, Michael D., Varner, Erika L., Bedi, Kenneth C., Bartee, David, Jiang, Helen, Trefely, Sophie, Xu, Peining, Singh, Jay P., Jang, Cholsoon, Rame, J. Eduardo, Brady, Donita C., Meier, Jordan L., Marguiles, Kenneth B., Arany, Zoltan, Snyder, Nathaniel W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9189226/
https://www.ncbi.nlm.nih.gov/pubmed/35568254
http://dx.doi.org/10.1016/j.jlr.2022.100224