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Overview of Checkpoint Inhibitors Mechanism of Action: Role of Immune-Related Adverse Events and Their Treatment on Progression of Underlying Cancer

In recent years, immunotherapy-based regimens have been included into the treatment's algorithm of several cancer types. Programmed death-1 (PD-1) and cytotoxic T lymphocyte antigen-4 (CTLA-4) interact with their ligands found on the surface of antigen presenting cells (APC) or tumor cells (PD-...

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Detalles Bibliográficos
Autores principales: Iranzo, Patricia, Callejo, Ana, Assaf, Juan David, Molina, Gaspar, Lopez, Daniel Esteban, Garcia-Illescas, David, Pardo, Nuria, Navarro, Alejandro, Martinez-Marti, Alex, Cedres, Susana, Carbonell, Caterina, Frigola, Joan, Amat, Ramon, Felip, Enriqueta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9189307/
https://www.ncbi.nlm.nih.gov/pubmed/35707528
http://dx.doi.org/10.3389/fmed.2022.875974