IM156, a new AMPK activator, protects against polymicrobial sepsis

IM156, a novel biguanide with higher potency of AMP‐activated protein kinase activation than metformin, has inhibitory activity against angiogenesis and cancer. In this study, we investigated effects of IM156 against polymicrobial sepsis. Administration of IM156 significantly increased survival rate...

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Detalles Bibliográficos
Autores principales: Kang, Ji Hyeon, Lee, Sung Kyun, Yun, Nam Joo, Kim, Ye Seon, Song, Jason Jungsik, Bae, Yoe‐Sik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9189331/
https://www.ncbi.nlm.nih.gov/pubmed/35502484
http://dx.doi.org/10.1111/jcmm.17341

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9189331/
https://www.ncbi.nlm.nih.gov/pubmed/35502484
http://dx.doi.org/10.1111/jcmm.17341

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