Salubrinal Protects Against Cisplatin-Induced Cochlear Hair Cell Endoplasmic Reticulum Stress by Regulating Eukaryotic Translation Initiation Factor 2α Signalling

OBJECTIVE: Cisplatin is a broad-spectrum anti-tumour drug commonly used in clinical practice. However, its ototoxicity greatly limits its clinical application, and no effective method is available to prevent this effect. Endoplasmic reticulum stress (ERS) is reportedly involved in cisplatin ototoxic...

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Detalles Bibliográficos
Autores principales: Lu, Wen, Ni, Kun, Li, Zhuangzhuang, Xiao, Lili, Li, Yini, Jiang, Yumeng, Zhang, Jincheng, Shi, Haibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9189388/
https://www.ncbi.nlm.nih.gov/pubmed/35706425
http://dx.doi.org/10.3389/fnmol.2022.916458

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9189388/
https://www.ncbi.nlm.nih.gov/pubmed/35706425
http://dx.doi.org/10.3389/fnmol.2022.916458

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