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Salubrinal Protects Against Cisplatin-Induced Cochlear Hair Cell Endoplasmic Reticulum Stress by Regulating Eukaryotic Translation Initiation Factor 2α Signalling
OBJECTIVE: Cisplatin is a broad-spectrum anti-tumour drug commonly used in clinical practice. However, its ototoxicity greatly limits its clinical application, and no effective method is available to prevent this effect. Endoplasmic reticulum stress (ERS) is reportedly involved in cisplatin ototoxic...
Autores principales: | Lu, Wen, Ni, Kun, Li, Zhuangzhuang, Xiao, Lili, Li, Yini, Jiang, Yumeng, Zhang, Jincheng, Shi, Haibo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9189388/ https://www.ncbi.nlm.nih.gov/pubmed/35706425 http://dx.doi.org/10.3389/fnmol.2022.916458 |
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